Back to search
Publication

Evaluation of anti-cardiolipin antibody and its cross-reactivity in sera of patients with lepromatous leprosy.

Abstract

Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with double-stranded (ds) DNA, but not with single-stranded (ss) DNA or extractable nuclear antigens (ENA). We describe the unique pattern of antibody cross-reactivity with cardiolipin and dsDNA in sera of patients with lepromatous leprosy.

More information

Type
Journal Article
Author
Furukawa F
Kashihara M
Imamura S
Ohshio G
Hamashima Y
Year of Publication
1986
Journal
Archives of dermatological research
Volume
278
Issue
4
Number of Pages
317-9
Date Published
1986
Language
eng
ISSN Number
0340-3696
DOI
10.1007/bf00407745
Alternate Journal
Arch. Dermatol. Res.
Publication Language
eng

More publications on: