TY - JOUR
KW - Antigens, Nuclear
KW - Autoantibodies
KW - Cardiolipins
KW - Cross Reactions
KW - DNA
KW - DNA, Single-Stranded
KW - Humans
KW - leprosy
KW - Nucleoproteins
AU - Furukawa F
AU - Kashihara M
AU - Imamura S
AU - Ohshio G
AU - Hamashima Y
AB - <p>Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with double-stranded (ds) DNA, but not with single-stranded (ss) DNA or extractable nuclear antigens (ENA). We describe the unique pattern of antibody cross-reactivity with cardiolipin and dsDNA in sera of patients with lepromatous leprosy.</p>
BT - Archives of dermatological research
C1 - http://www.ncbi.nlm.nih.gov/pubmed/3740940?dopt=Abstract
DA - 1986
DO - 10.1007/bf00407745
IS - 4
J2 - Arch. Dermatol. Res.
LA - eng
N2 - <p>Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with double-stranded (ds) DNA, but not with single-stranded (ss) DNA or extractable nuclear antigens (ENA). We describe the unique pattern of antibody cross-reactivity with cardiolipin and dsDNA in sera of patients with lepromatous leprosy.</p>
PY - 1986
SP - 317
EP - 9
T2 - Archives of dermatological research
TI - Evaluation of anti-cardiolipin antibody and its cross-reactivity in sera of patients with lepromatous leprosy.
VL - 278
SN - 0340-3696
ER -