01282nas a2200289   4500000000100000008004100001260000900042653002200051653001900073653001700092653002000109653000800129653002500137653001100162653001200173653001900185100001500204700001600219700001400235700001300249700001600262245011500278300001000393490000800403520056700411022001400978       1986                            d  c198610aAntigens, Nuclear10aAutoantibodies10aCardiolipins10aCross Reactions10aDNA10aDNA, Single-Stranded10aHumans10aleprosy10aNucleoproteins1 aFurukawa F1 aKashihara M1 aImamura S1 aOhshio G1 aHamashima Y00aEvaluation of anti-cardiolipin antibody and its cross-reactivity in sera of patients with lepromatous leprosy.  a317-90 v2783 a<p>Using a sensitive and modified solid-phase radioimmunoassay for detecting anti-cardiolipin antibodies, sera of 45 patients with lepromatous leprosy were examined. Nine of the 45 (20%) showed positive levels of anti-cardiolipin antibodies. Inhibition tests revealed that these antibodies significantly cross-reacted with double-stranded (ds) DNA, but not with single-stranded (ss) DNA or extractable nuclear antigens (ENA). We describe the unique pattern of antibody cross-reactivity with cardiolipin and dsDNA in sera of patients with lepromatous leprosy.</p>  a0340-3696