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Publication

Absence of nucleotide-binding oligomerization domain-containing protein 2 variants in patients with leprosy and tuberculosis.

Abstract

Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states. This is the first report to suggest the minimal role of these variants in susceptibility/resistance to TB and leprosy in this population.

More information

Type
Journal Article
Author
Singh V
Gaur R
Mittal M
Biswas S K
Das R
Girdhar B K
Bajaj B
Katoch V M
Kumar A
Mohanty K K
Country
UK
Year of Publication
2012
Journal
International journal of immunogenetics
Volume
39
Issue
4
Number of Pages
353-6
Date Published
2012 Aug
Language
eng
ISSN Number
1744-313X
DOI
10.1111/j.1744-313X.2012.01085.x
Alternate Journal
Int. J. Immunogenet.
Publication Language
eng