01726nas a2200493   4500000000100000008004100001260004800042653001000090653002500100653001100125653001900136653003200155653003000187653003800217653002000255653002600275653001700301653001100318653001000329653001200339653000900351653001600360653001800376653003500394653001500429653003600444653001700480653001600497100001200513700001100525700001300536700001500549700001000564700001600574700001200590700001500602700001200617700001600629245013000645300001000775490000700785520042600792022001401218       2012                            d  c2012 AugbBlackwell Publishing Ltd.aOxford10aAdult10aCase-Control Studies10aFemale10aGene Frequency10aGenetic Association Studies10aGenetic Carrier Screening10aGenetic Predisposition to Disease10aGenetic Testing10aGenotyping Techniques10aHeterozygote10aHumans10aIndia10aleprosy10aMale10aMiddle Aged10aMycobacterium10aNod2 Signaling Adaptor Protein10aOdds Ratio10aPolymorphism, Single Nucleotide10aTuberculosis10aYoung Adult1 aSingh V1 aGaur R1 aMittal M1 aBiswas S K1 aDas R1 aGirdhar B K1 aBajaj B1 aKatoch V M1 aKumar A1 aMohanty K K00aAbsence of nucleotide-binding oligomerization domain-containing protein 2 variants in patients with leprosy and tuberculosis.  a353-60 v393 a<p>Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states. This is the first report to suggest the minimal role of these variants in susceptibility/resistance to TB and leprosy in this population.</p>  a1744-313X