TY - JOUR
KW - Adult
KW - Case-Control Studies
KW - Female
KW - Gene Frequency
KW - Genetic Association Studies
KW - Genetic Carrier Screening
KW - Genetic Predisposition to Disease
KW - Genetic Testing
KW - Genotyping Techniques
KW - Heterozygote
KW - Humans
KW - India
KW - leprosy
KW - Male
KW - Middle Aged
KW - Mycobacterium
KW - Nod2 Signaling Adaptor Protein
KW - Odds Ratio
KW - Polymorphism, Single Nucleotide
KW - Tuberculosis
KW - Young Adult
AU - Singh V
AU - Gaur R
AU - Mittal M
AU - Biswas S K
AU - Das R
AU - Girdhar B K
AU - Bajaj B
AU - Katoch V M
AU - Kumar A
AU - Mohanty K K
AB - <p>Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states. This is the first report to suggest the minimal role of these variants in susceptibility/resistance to TB and leprosy in this population.</p>
BT - International journal of immunogenetics
C1 - http://www.ncbi.nlm.nih.gov/pubmed/22289211?dopt=Abstract
C2 - UK
CY - Oxford
DA - 2012 Aug
DO - 10.1111/j.1744-313X.2012.01085.x
IS - 4
J2 - Int. J. Immunogenet.
LA - eng
N2 - <p>Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states. This is the first report to suggest the minimal role of these variants in susceptibility/resistance to TB and leprosy in this population.</p>
PB - Blackwell Publishing Ltd.
PP - Oxford
PY - 2012
SP - 353
EP - 6
T2 - International journal of immunogenetics
TI - Absence of nucleotide-binding oligomerization domain-containing protein 2 variants in patients with leprosy and tuberculosis.
VL - 39
SN - 1744-313X
ER -