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Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort.

Abstract

Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.

More information

Type
Journal Article
Author
Menezes VM
Sales AM
Illarramendi X
Miranda A
Gonçalves Morgado M
Gutierrez-Galhardo MC
Nunes Sarno E
Costa Nery JA
Year of Publication
2009
Journal
AIDS (London, England)
Volume
23
Issue
5
Number of Pages
641-3
Date Published
2009 Mar 13
Language
eng
ISSN Number
1473-5571
DOI
10.1097/QAD.0b013e3283291405
Alternate Journal
AIDS
Publication Language
eng