TY - JOUR KW - Adult KW - Antiretroviral Therapy, Highly Active KW - Cohort Studies KW - Female KW - HIV Infections KW - Humans KW - Immune Reconstitution Inflammatory Syndrome KW - leprosy KW - Male KW - Middle Aged KW - Young Adult AU - Menezes VM AU - Sales A AU - Illarramendi X AU - Miranda A AU - Morgado MG AU - Gutierrez-Galhardo MC AU - Sarno E AU - Costa Nery JA AB -

Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.

BT - AIDS (London, England) C1 - http://www.ncbi.nlm.nih.gov/pubmed/19525622?dopt=Abstract DA - 2009 Mar 13 DO - 10.1097/QAD.0b013e3283291405 IS - 5 J2 - AIDS LA - eng N2 -

Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.

PY - 2009 SP - 641 EP - 3 T2 - AIDS (London, England) TI - Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort. VL - 23 SN - 1473-5571 ER -