01479nas a2200349 4500000000100000008004100001260001600042653001000058653004200068653001900110653001100129653001900140653001100159653004800170653001200218653000900230653001600239653001600255100001500271700001200286700001900298700001400317700001500331700002600346700001200372700001800384245012500402300001000527490000700537520057100544022001401115 2009 d c2009 Mar 1310aAdult10aAntiretroviral Therapy, Highly Active10aCohort Studies10aFemale10aHIV Infections10aHumans10aImmune Reconstitution Inflammatory Syndrome10aleprosy10aMale10aMiddle Aged10aYoung Adult1 aMenezes VM1 aSales A1 aIllarramendi X1 aMiranda A1 aMorgado MG1 aGutierrez-Galhardo MC1 aSarno E1 aCosta Nery JA00aLeprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort. a641-30 v233 a
Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.
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