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Publication

Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil.

Abstract

INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce.

METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases.

RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases.

CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.

More information

Type
Journal Article
Author
Vernal S
Bueno-Filho R
Gomes CM
Roselino AM
Year of Publication
2019
Journal
Revista da Sociedade Brasileira de Medicina Tropical
Volume
52
Number of Pages
e20180172
Language
eng
ISSN Number
1678-9849
DOI
10.1590/0037-8682-0172-2018
Alternate Journal
Rev. Soc. Bras. Med. Trop.
Publication Language
eng