|Title||Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil.|
|Publication Type||Journal Article|
|Authors||Vernal S, Bueno-Filho R, Gomes CM, Roselino AM|
|Abbrev. Journal||Rev. Soc. Bras. Med. Trop.|
|Journal||Revista da Sociedade Brasileira de Medicina Tropical|
|Year of Publication||2019|
INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce.
METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases.
RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases.
CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.
|Link to full text||http://www.scielo.br/pdf/rsbmt/v52/1678-9849-rsbmt-52-e20180172.pdf|