01364nas a2200169   4500000000100000008004100001100001300042700001800055700001300073700001600086245013600102856007200238300001400310490000700324520084900331022001401180       2019                            d1 aVernal S1 aBueno-Filho R1 aGomes CM1 aRoselino AM00aClinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil.  uhttp://www.scielo.br/pdf/rsbmt/v52/1678-9849-rsbmt-52-e20180172.pdf  ae201801720 v523 a<p><strong>INTRODUCTION: </strong>American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce.</p>

<p><strong>METHODS: </strong>We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases.</p>

<p><strong>RESULTS: </strong>Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases.</p>

<p><strong>CONCLUSIONS: </strong>The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.</p>
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