@article{33145, author = {Vernal S and Bueno-Filho R and Gomes CM and Roselino AM}, title = {Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil.}, abstract = {

INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce.

METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases.

RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases.

CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.

}, year = {2019}, journal = {Revista da Sociedade Brasileira de Medicina Tropical}, volume = {52}, pages = {e20180172}, issn = {1678-9849}, url = {http://www.scielo.br/pdf/rsbmt/v52/1678-9849-rsbmt-52-e20180172.pdf}, doi = {10.1590/0037-8682-0172-2018}, language = {eng}, }