Cellular immune response to common mycobacterial antigens in subjects seropositive for Trypanosoma cruzi.

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TitleCellular immune response to common mycobacterial antigens in subjects seropositive for Trypanosoma cruzi.
Publication TypeJournal Article
AuthorsBottasso OA, Ingledew N, Keni M, Morini J, Pividori JF, Rook GA, Stanford JL
Abbrev. JournalLancet
JournalLancet (London, England)
Year of Publication1994
Volume344
Issue8936
Pagination1540-1
Publication Languageeng
KeywordsAdult, Animals, Antigens, Protozoan, Chagas Disease, Female, Humans, Immunity, Cellular, Male, Mycobacterium bovis, Skin Tests, Trypanosoma cruzi, Tuberculin Test
Abstract

The immune response is impaired in the silent stage of Chagas' disease. We used quadruple skin-testing with new tuberculins in 37 adults who were symptom-free but seropositive for Trypanosoma cruzi and in 37 matched seronegative controls. Whereas 19% of controls responded to common mycobacterial antigens, none of the Chagas' seropositive group responded to them (p

PubMed URL

http://www.ncbi.nlm.nih.gov/pubmed/7983955?dopt=Abstract

DOI10.1016/s0140-6736(94)90351-4

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