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Publication

Ocular findings in leprosy patients in Nepal in the era of multidrug therapy.

Abstract

PURPOSE: Detailed ophthalmic evaluation was performed to determine the prevalence of ocular complications among leprosy patients on multidrug therapy and those released from multidrug treatment.

DESIGN: Observational case series.

METHODS: Leprosy patients at Tribhuvan University Teaching Hospital from April 1, 2001, through September 30, 2002, underwent detailed ophthalmic evaluation including slit-lamp biomicroscopy, dilated funduscopy, and applanation tonometry.

RESULTS: We evaluated 58 leprosy patients. A majority (72%) was receiving treatment for multibacillary leprosy; 14% belonged to posttreatment multibacillary and paucibacillary groups. Ocular involvement was found in 57% of patients. In the multibacillary group, 55% had ocular involvement, which was more than double that found in the paucibacillary group (25%), although this finding was not statistically significant (P =.187). Among patients with ocular complications, 48% had visual disability and another 45% had threatened vision; 9% met World Health Organization guidelines for blindness. Uveitis and its complications were the predominant causes of visual disability (88%).

CONCLUSION: Ocular complications and visual disability are high among leprosy patients in Nepal even after completing multidrug therapy.

More information

Type
Journal Article
Author
Nepal BP
Shrestha UD
Year of Publication
2004
Journal
American journal of ophthalmology
Volume
137
Issue
5
Number of Pages
888-92
Date Published
2004 May
Language
eng
ISSN Number
0002-9394
DOI
10.1016/j.ajo.2003.12.048
Alternate Journal
Am. J. Ophthalmol.
Publication Language
eng