@article{791, keywords = {Adult, Drug Therapy, Combination, Eye diseases, Female, Humans, Leprostatic Agents, leprosy, Male, Middle Aged, Nepal, Prevalence}, author = {Nepal B and Shrestha UD}, title = {Ocular findings in leprosy patients in Nepal in the era of multidrug therapy.}, abstract = {

PURPOSE: Detailed ophthalmic evaluation was performed to determine the prevalence of ocular complications among leprosy patients on multidrug therapy and those released from multidrug treatment.

DESIGN: Observational case series.

METHODS: Leprosy patients at Tribhuvan University Teaching Hospital from April 1, 2001, through September 30, 2002, underwent detailed ophthalmic evaluation including slit-lamp biomicroscopy, dilated funduscopy, and applanation tonometry.

RESULTS: We evaluated 58 leprosy patients. A majority (72%) was receiving treatment for multibacillary leprosy; 14% belonged to posttreatment multibacillary and paucibacillary groups. Ocular involvement was found in 57% of patients. In the multibacillary group, 55% had ocular involvement, which was more than double that found in the paucibacillary group (25%), although this finding was not statistically significant (P =.187). Among patients with ocular complications, 48% had visual disability and another 45% had threatened vision; 9% met World Health Organization guidelines for blindness. Uveitis and its complications were the predominant causes of visual disability (88%).

CONCLUSION: Ocular complications and visual disability are high among leprosy patients in Nepal even after completing multidrug therapy.

}, year = {2004}, journal = {American journal of ophthalmology}, volume = {137}, pages = {888-92}, month = {2004 May}, issn = {0002-9394}, doi = {10.1016/j.ajo.2003.12.048}, language = {eng}, }