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Nerve abscess in Hansen's disease as part of immune reconstitution inflammatory syndrome: a case report.

Abstract

Immune reconstitution inflammatory syndrome is an inflammatory reaction in HIV-infected patients after initiation of antiretroviral therapy resulting from restored immunity to specific infectious or non-infectious antigens. A 36-year-old male patient on highly active antiretroviral therapy of six months duration, presented with reddish, tender lesions over medial aspect of arm and a single, anaesthetic patch. Tender fluctuant swellings were seen on the medial aspect of left forearm. A few of them had ruptured spontaneously discharging pus. A skin biopsy from the anaesthetic patch showed caseating epitheloid granulomas. A diagnosis of Hansen's disease borderline tuberculoid in type 1 reversal reaction, with formation of nerve abscess due to Immune Reconstitution Inflammatory Syndrome was made. The patient was started on multibacillary multidrug therapy as per WHO guidelines and highly active antiretroviral therapy was continued.

More information

Type
Journal Article
Author
Ali NM
Nayak K
Kumar P
Year of Publication
2016
Journal
International journal of STD & AIDS
Language
eng
ISSN Number
1758-1052
DOI
10.1177/0956462416654069
Alternate Journal
Int J STD AIDS
Publication Language
eng