01405nas a2200169   4500000000100000008004100001653001200042653000900054653001000063653004900073100001100122700001200133700001200145245010900157520095500266022001401221       2016                            d10aleprosy10aAids10aIndia10aHighly active antiretroviral therapy (HAART)1 aAli NM1 aNayak K1 aKumar P00aNerve abscess in Hansen's disease as part of immune reconstitution inflammatory syndrome: a case report.3 a<p>Immune reconstitution inflammatory syndrome is an inflammatory reaction in HIV-infected patients after initiation of antiretroviral therapy resulting from restored immunity to specific infectious or non-infectious antigens. A 36-year-old male patient on highly active antiretroviral therapy of six months duration, presented with reddish, tender lesions over medial aspect of arm and a single, anaesthetic patch. Tender fluctuant swellings were seen on the medial aspect of left forearm. A few of them had ruptured spontaneously discharging pus. A skin biopsy from the anaesthetic patch showed caseating epitheloid granulomas. A diagnosis of Hansen's disease borderline tuberculoid in type 1 reversal reaction, with formation of nerve abscess due to Immune Reconstitution Inflammatory Syndrome was made. The patient was started on multibacillary multidrug therapy as per WHO guidelines and highly active antiretroviral therapy was continued.</p>
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