Facial sensory loss in multi-bacillary leprosy patients.

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TitleFacial sensory loss in multi-bacillary leprosy patients.
Publication TypeJournal Article
AuthorsDaniel E, Rao PSS, Courtright P
Abbrev. JournalLepr Rev
JournalLeprosy review
Year of Publication2013
Publication Languageeng
KeywordsAdolescent, Adult, Aged, Child, Cohort Studies, Eyelids, Face, Facial Nerve Diseases, Female, Humans, Leprosy, Multibacillary, Logistic Models, Longitudinal studies, Male, Middle Aged

Sensation over the face was estimated using the Semmes-Weinstein's monofilament (target force 0-05 gms) in a cohort of multi-bacillary (MB) patients whose clinical and ocular characteristics were available at the time of leprosy diagnosis. Among the 190 MB patients examined, 56 (30%) had areas of sensory impairment somewhere on the face and 43 (23%) had sensory deficit over the lids and/or the malar area. Lagophthalmos (adjusted OR 8.96, 95% CI 0.96-83.50), Type 1 reaction (aOR 2.47, 95% CI 1.11-5-52), history of reactions (aOR 6.36, 95% CI 2.40-16.85) and glove and stocking anaesthesia (aOR 3.49, 95% CI 1-40-8.70) were associated with impaired facial sensation. Hypoesthesia restricted to areas over the lids and/or malar area showed a stronger association with lagophthalmos (aOR 17.5, 95% CI 1.98-154.36). Loss of facial sensation appears to be associated with lagophthalmos in MB patients.

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Link to full texthttp://www.lepra.org.uk/platforms/lepra/files/lr/Sept13/1762.pdf