01712nas a2200337 4500000000100000008004100001653001600042653000900058653002500067653002000092653002800112653001100140653001100151653002600162653000900188653001200197653001900209653001000228653000900238653001000247653001500257100001300272700001400285700001700299245006100316856005100377300001000428490000700438520091500445022001401360 2013 d10aMiddle Aged10aMale10aLongitudinal studies10aLogistic Models10aLeprosy, Multibacillary10aHumans10aFemale10aFacial Nerve Diseases10aFace10aEyelids10aCohort Studies10aChild10aAged10aAdult10aAdolescent1 aDaniel E1 aRao P S S1 aCourtright P00aFacial sensory loss in multi-bacillary leprosy patients. uhttps://leprosyreview.org/article/84/3/19-4198 a194-80 v843 a

Sensation over the face was estimated using the Semmes-Weinstein's monofilament (target force 0-05 gms) in a cohort of multi-bacillary (MB) patients whose clinical and ocular characteristics were available at the time of leprosy diagnosis. Among the 190 MB patients examined, 56 (30%) had areas of sensory impairment somewhere on the face and 43 (23%) had sensory deficit over the lids and/or the malar area. Lagophthalmos (adjusted OR 8.96, 95% CI 0.96-83.50), Type 1 reaction (aOR 2.47, 95% CI 1.11-5-52), history of reactions (aOR 6.36, 95% CI 2.40-16.85) and glove and stocking anaesthesia (aOR 3.49, 95% CI 1-40-8.70) were associated with impaired facial sensation. Hypoesthesia restricted to areas over the lids and/or malar area showed a stronger association with lagophthalmos (aOR 17.5, 95% CI 1.98-154.36). Loss of facial sensation appears to be associated with lagophthalmos in MB patients.

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