Borderline tuberculoid Hansen's disease in AIDS.

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TitleBorderline tuberculoid Hansen's disease in AIDS.
Publication TypeJournal Article
AuthorsGoodless DR, Viciana AL, Pardo RJ, Ruiz P
Abbrev. JournalJ. Am. Acad. Dermatol.
JournalJournal of the American Academy of Dermatology
Year of Publication1994
Issue5 Pt 2
Publication Languageeng
KeywordsAIDS-Related Opportunistic Infections, Antigens, CD, Antigens, CD1, HLA-DR Antigens, Humans, Leprosy, Borderline, Leprosy, Tuberculoid, Male, Middle Aged, Receptors, Interleukin-2, Skin

We performed an immunohistochemical analysis of a skin lesion from a patient with AIDS who had borderline tuberculoid Hansen's disease. We also evaluated other laboratory features and performed peripheral blood flow cytometric analysis. The in situ immunologic response to Mycobacterium leprae was minimally affected by concomitant infection and immunosuppression by HIV. The skin demonstrated the typical characteristics of borderline tuberculoid lesions. These results indicate that although a patient with HIV infection may have laboratory evidence typical of the immunosuppression seen in AIDS, the immunologic response to M. leprae is essentially unchanged.

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