We performed an immunohistochemical analysis of a skin lesion from a patient with AIDS who had borderline tuberculoid Hansen's disease. We also evaluated other laboratory features and performed peripheral blood flow cytometric analysis. The in situ immunologic response to Mycobacterium leprae was minimally affected by concomitant infection and immunosuppression by HIV. The skin demonstrated the typical characteristics of borderline tuberculoid lesions. These results indicate that although a patient with HIV infection may have laboratory evidence typical of the immunosuppression seen in AIDS, the immunologic response to M. leprae is essentially unchanged.
BT - Journal of the American Academy of Dermatology C1 - http://www.ncbi.nlm.nih.gov/pubmed/7513328?dopt=Abstract DA - 1994 May DO - 10.1016/s0190-9622(94)70101-6 IS - 5 Pt 2 J2 - J. Am. Acad. Dermatol. LA - eng N2 -We performed an immunohistochemical analysis of a skin lesion from a patient with AIDS who had borderline tuberculoid Hansen's disease. We also evaluated other laboratory features and performed peripheral blood flow cytometric analysis. The in situ immunologic response to Mycobacterium leprae was minimally affected by concomitant infection and immunosuppression by HIV. The skin demonstrated the typical characteristics of borderline tuberculoid lesions. These results indicate that although a patient with HIV infection may have laboratory evidence typical of the immunosuppression seen in AIDS, the immunologic response to M. leprae is essentially unchanged.
PY - 1994 SP - 866 EP - 9 T2 - Journal of the American Academy of Dermatology TI - Borderline tuberculoid Hansen's disease in AIDS. VL - 30 SN - 0190-9622 ER -