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What is New in the Pathogenesis and Management of Erythema Nodosum Leprosum.

Abstract

Erythema nodosum leprosum (ENL) is a manifestation of type II lepra reaction, seen in lepromatous or borderline lepromatous leprosy. Although it is a common reaction encountered in clinical practice, there are an increasingly large number of newer updates in the pathophysiology and management of this condition. The treatment options have expanded far beyond just thalidomide and steroids and now extends to TNF-α inhibitors, thalidomide analogs, tenidap, cyclosporine A, plasma exchange, and even IVIG amongst others. These updates and the current knowledge of ENL are summarized in this review.

More information

Type
Journal Article
Author
Bhat R
Vaidya T
Year of Publication
2020
Journal
Indian dermatology online journal
Volume
11
Issue
4
Number of Pages
482-492
Date Published
01/2020
Language
eng
ISSN Number
2229-5178
DOI
10.4103/idoj.IDOJ_561_19
Alternate Journal
Indian Dermatol Online J
PMID
32832433
Publication Language
eng