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Validity and reliability of the NEI VFQ-25 questionnaire in Indonesian leprosy patients



The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) is one of the most frequently used questionnaires to assess visual function. However, its validity and reliability have not been documented in specific context of use in leprosy patients.


To provide additional support to the reliability and validity of the NEI VFQ-25 in leprosy patients.


The reliability was assessed using internal consistency analysis (Cronbach's α formula). For validity assessment, item analysis was conducted by calculating the coefficient of corrected item-total correlation.


The result showed all items included in the analysis were considered valid, as the coefficient was >0.3. Internal consistency reliability (calculation of all the questions taken together), the Cronbach's α of the instrument was 0.934 and 0.937. Due to low socioeconomic and low educational status, the majority of the patients have no vehicles nor can drive, therefore, there is a high missing rate of ‘Driving’ subscale.


The NEI VFQ-25 is a reliable and valid instrument, and can be used to assess vision-related quality of life in Indonesian leprosy patients.

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Journal Article
Rahayu T
Menaldi SL
Irawati Y
Adriono GA
Presialia A
Harini M
Friska D