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Undernutrition and lepromatous leprosy. III. Micronutrients and their transport proteins.

Abstract

The present report is a continuation of our earlier studies on the complex interaction between undernutrition and leprosy. Serum levels of vitamins A and E, zinc and iron were determined in healthy control subjects and lepromatous leprosy patients belonging to an eastern state of India. Results indicated a significant lowering in the two above-mentioned fat-soluble vitamins and also a remarkable hypozincaemia in the patient group. However, serum iron levels were found to be comparable in both the groups. Also concentrations of vitamin A transport proteins such as retinol binding protein and prealbumin in sera of the lepromatous patients were significantly decreased in comparison with the control subjects. Of the two zinc-binding proteins, ie, serum albumin and alpha-2 macroglobulin, only the former was significantly reduced in the patient group. Surprisingly, though serum iron, transferrin and ferritin levels were similar in both the patient and control groups, the haemoglobin levels were significantly reduced in the lepromatous patients. The implications of these findings have been discussed. This is the first report describing the serum ferritin levels in lepromatous patients.

More information

Type
Journal Article
Author
Rao K N
Saha K
Chakrabarty A K
Year of Publication
1987
Journal
Human nutrition. Clinical nutrition
Volume
41
Issue
2
Number of Pages
127-34
Date Published
1987 Mar
Language
eng
ISSN Number
0263-8290
Alternate Journal
Hum Nutr Clin Nutr
Publication Language
eng

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