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Recurrent scleritis in lepromatous leprosy.

Abstract

BACKGROUND: Recurrent immune-mediated scleritis after adequate treatment of leprosy is not well documented in the literature. We describe an Australian resident with unilateral intra-ocular lepromatous leprosy who had persistent non-infectious scleritis.

METHODS: A man of Anglo-Indian ancestry initially presented with lepromatous leprosy and unilateral ocular involvement. The affected eye had an interstitial keratitis and a granulomatous anterior uveitis that responded to antileprotics and anti-inflammatory agents. Despite systemic cure with triple antileprotic therapy, he developed recurrent scleritis that required multiple scleral patch grafts for scleral thinning and, subsequently, an enucleation. Histology failed to demonstrate persistent infection, rather a chronic non-granulomatous scleritis, which was probably immune mediated.

RESULTS/CONCLUSIONS: This case demonstrates an ocular complication of leprosy that is infrequently reported. Patients with ocular involvement by leprosy are at risk of developing recurrent scleritis despite systemic cure with antileprotics.

More information

Type
Journal Article
Author
Poon A
MacLean H
McKelvie P
Year of Publication
1998
Journal
Australian and New Zealand journal of ophthalmology
Volume
26
Issue
1
Number of Pages
51-5
Date Published
1998 Feb
Language
eng
ISSN Number
0814-9763
Alternate Journal
Aust N Z J Ophthalmol
Publication Language
eng

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