Neuropathophysiology in Morbus Hansen or Hansen’s Disease: Mechanisms of Nerve Injury

This chapter discusses possible mechanisms of nerve damage during infection with Mycobacterium leprae. It examines the damage caused by immunological as well as by physical factors. It looks at the nerve damage in patients with Morbus Hansen and in their contacts. It discusses the damage caused by reactions in Hansen’s disease, Type 1, and Type 2 (Reversal Reaction and Erythema Nodosum Leprosum). Autoimmunity is suggested as a possible driving force for reactions.