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T-lymphocyte subsets in leprosy.
Abstract
Immunologic abnormalities in T cells have been reported in patients with lepromatous leprosy. Ten patients with leprosy (eight lepromatous, one dimorphous, one tuberculoid) were studied in order to detect the proportions of total T lymphocytes and helper as well as suppressor subsets, using monoclonal antibodies in an indirect immunofluorescence test. Percentages of total T cells, suppressor cells, as well as helper subsets were similar in leprosy patients as compared with age-matched controls. This study could be considered a preliminary one to be followed by functional assays.
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Type
Journal Article