Screening of scalp infection and antifungal activity of commercially available shampoo against the isolates among the leprosy patients

Leprosy affects mainly those areas of skin which have a relatively lower temperature and are more exposed to trauma. Certain zones like scalp, palms and soles, genitalia, groins, axillae, eyelids, transverse band of skin over lumbosacral area, midline of back and perineum have been described to be immune to the development of lesion. . Tinea capititis (scalp ringworm) is a cutaneous fungal infection (dermatophytosis) of the scalp. The diseases is primarily caused by dermatophytes in the Trichophyton and Microsporum genera that invade the hair shaft. Fifty volunteer leprosy patients were subject to the study. The scalp samples were collected and plated on Potato Dextrose Agar plates. Commercially available shampoos were screened for antifungal activity and shows significant activity. The antifungal sensitivity for the isolates were tested and found to exhibit drug resistant.