Paucibacillary leprosy patients treated with multidrug therapy four years experience (1988 to 1991) in Bangladesh.

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TitlePaucibacillary leprosy patients treated with multidrug therapy four years experience (1988 to 1991) in Bangladesh.
Publication TypeJournal Article
AuthorsFaruque E, Hoque AK, Ahmed J, Ahmed R, Ali A
Abbrev. JournalNihon Rai Gakkai Zasshi
JournalNihon Rai Gakkai zasshi
Year of Publication1994
Volume63
Issue3
Pagination95-8
Publication Languageeng
KeywordsAdolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Bangladesh, Child, Dapsone, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Leprosy, Male, Middle Aged, Rifampin
Abstract

Two hundred and fifty paucibacillary (PB) leprosy patients were treated with WHO recommended multidrug therapy (MDT) and followed up them for four years. The paucibacillary MDT regimen (PBR) was well accepted and tolerated by the patients. Clinical regression was attained in 60% patients after 6 doses of PBR. Reversal reaction occurred in 14% cases and relapse were found in 1.6% cases 18-24 months after completing the treatment. The incidence of reversal reaction was high in patients with more than 2 thickened nerve trunks associated with more than 5 patches.

PubMed URL

http://www.ncbi.nlm.nih.gov/pubmed/7730212?dopt=Abstract