Genetic diathesis for leprosy.

Innate incapacity to elaborate a protective cellular immunity has been thought to underlie the evaluation of the disease process of lepromatous leprosy. Although both family and twin studies were suggestive of the involvement of some genetic factors, they have so far not been evaluated fully. Keeping this in view, the present study, conducted at the family level, was designed to evaluate the role of genetic factors in determining the type of leprosy in a patient.