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Antileprosy activity and preliminary toxicological characteristics of some dialkyldithiocarbamate derivatives.

Abstract

Antileprosy activity of dialkyldithiocarbamate derivatives was studied in experiments on mice infected with M. leprae into paw pads. We found that 2-diethyldithiocarbamoyl-3-cyano-5-nitropyridine is the most promising antileprosy agent; it effectively suppresses multiplication of M. leprae and is well tolerated under conditions of chronic animal experiment.

More information

Type
Journal Article
Author
Urlyapova N G
Yuschenko A A
Daudova A D
Makarov V A

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