Paucibacillary leprosy patients treated with multidrug therapy four years experience (1988 to 1991) in Bangladesh.

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TítuloPaucibacillary leprosy patients treated with multidrug therapy four years experience (1988 to 1991) in Bangladesh.
Tipo de PublicaçãoJournal Article
AutoresFaruque E, Hoque AK, Ahmed J, Ahmed R, Ali A
Abbrev. JournalNihon Rai Gakkai Zasshi
RevistaNihon Rai Gakkai zasshi
Ano de Publicação1994
Volume63
Issue3
Pagination95-8
Idioma da Publicaçãoeng
Palavras-chave Adolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Bangladesh, Child, Dapsone, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Leprosy, Male, Middle Aged, Rifampin
Resumo

Two hundred and fifty paucibacillary (PB) leprosy patients were treated with WHO recommended multidrug therapy (MDT) and followed up them for four years. The paucibacillary MDT regimen (PBR) was well accepted and tolerated by the patients. Clinical regression was attained in 60% patients after 6 doses of PBR. Reversal reaction occurred in 14% cases and relapse were found in 1.6% cases 18-24 months after completing the treatment. The incidence of reversal reaction was high in patients with more than 2 thickened nerve trunks associated with more than 5 patches.

PubMed URL

http://www.ncbi.nlm.nih.gov/pubmed/7730212?dopt=Abstract