@article{5681,
  keywords = {Bacterial Vaccines, Case-Control Studies, Female, Humans, leprosy, Male, Mycobacterium leprae},
  author = {Bhatki W S and Chulawala R G},
  title = {Immunotherapeutic potential of ICRC vaccine: a case control study.},
  abstract = {<p>A bacteriological follow-up of 16 lepromatous patients with a high initial Bacteriological Index (BI) showed that in 8 randomly selected patients who received single doses of ICRC Vaccine (C44) at the onset of multidrug therapy, the average reduction of BI was from 4.4+ to 1+ in 2 years--3 of these patients became negative and 3 showed BI 1+ or less. Comparable bacteriological assessments in 8 non-vaccinated but otherwise similar patients showed an average reduction of BI from 4.7+ to 2.6+, i.e. consistent with the expected response to MDT in lepromatous patients. Here we discuss the role of immunotherapy and the selection of a desirable antileprosy vaccine in the context of fixed-duration MDT.</p>},
  year = {1992},
  journal = {Leprosy review},
  volume = {63},
  pages = {358-64},
  month = {1992 Dec},
  issn = {0305-7518},
  url = {http://leprev.ilsl.br/pdfs/1992/v63n4/pdf/v63n4a08.pdf},
  language = {eng},
}