Twenty-five patients of bacilliferous leprosy (17 LL, 8 BL) were studied by the modified haemolysis method for occurrence of bacillaemia and its clearance after two multidrug therapy regimens. Acid-fast bacilli were found in 76% of all patients and in 88.2% LL and 50% BL patients. Bacillaemia occurred with significantly reduced frequency in patients with type II reaction. Acid-fast bacilli were demonstrable in peripheral blood after 1 month in one patient on MDT of an Indian Working Group and 3 lepromatous patients on WHO multidrug therapy. However, bacillaemia could not be demonstrated in any patients after 2 and 3 months of treatment with both regimens.
BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/2682105?dopt=Abstract CN - CHATTERJEE 1989 DA - 1989 Sep DO - 10.5935/0305-7518.19890025 IS - 3 J2 - Lepr Rev LA - eng N2 -Twenty-five patients of bacilliferous leprosy (17 LL, 8 BL) were studied by the modified haemolysis method for occurrence of bacillaemia and its clearance after two multidrug therapy regimens. Acid-fast bacilli were found in 76% of all patients and in 88.2% LL and 50% BL patients. Bacillaemia occurred with significantly reduced frequency in patients with type II reaction. Acid-fast bacilli were demonstrable in peripheral blood after 1 month in one patient on MDT of an Indian Working Group and 3 lepromatous patients on WHO multidrug therapy. However, bacillaemia could not be demonstrated in any patients after 2 and 3 months of treatment with both regimens.
PY - 1989 SP - 197 EP - 201 T2 - Leprosy review TI - Bacillaemia in leprosy and effect of multidrug therapy. UR - http://leprev.ilsl.br/pdfs/1989/v60n3/pdf/v60n3a04.pdf VL - 60 SN - 0305-7518 ER -