A woman in her early 60s treated for Hansen disease 20 years ago presented with diminution of vision in both eyes for the past year. Her best-corrected visual acuity was 6/24 OU. A moth-eaten pattern of iris atrophy was noted bilaterally. Iris atrophy has been reported to be the most common ocular lesion in chronic multibacillary leprosy (25% of patients), persisting despite adequate treatment (3% of patients). The patient’s lens showed cataractous changes in both eyes with a normal posterior segment as evidenced on B-scan ultrasonography. Corneal sensation measured with a Cochet-Bonne esthesiometer was 55 mm OD and 50 mm OS (mean [SD] normal sensation, 57.50 [3.41] mm). Clinical images (slitlamp and near-infrared autofluorescence photographs) showed a moth-eaten appearance of the iris in a case of resolved chronic bilateral anterior uveitis with decreased corneal sensation, which is probably a sequela of Hansen disease.
BT - JAMA ophthalmology C1 -https://www.ncbi.nlm.nih.gov/pubmed/37971507
DA - 11/2023 DO - 10.1001/jamaophthalmol.2023.2470 IS - 11 J2 - JAMA Ophthalmol LA - eng N2 -A woman in her early 60s treated for Hansen disease 20 years ago presented with diminution of vision in both eyes for the past year. Her best-corrected visual acuity was 6/24 OU. A moth-eaten pattern of iris atrophy was noted bilaterally. Iris atrophy has been reported to be the most common ocular lesion in chronic multibacillary leprosy (25% of patients), persisting despite adequate treatment (3% of patients). The patient’s lens showed cataractous changes in both eyes with a normal posterior segment as evidenced on B-scan ultrasonography. Corneal sensation measured with a Cochet-Bonne esthesiometer was 55 mm OD and 50 mm OS (mean [SD] normal sensation, 57.50 [3.41] mm). Clinical images (slitlamp and near-infrared autofluorescence photographs) showed a moth-eaten appearance of the iris in a case of resolved chronic bilateral anterior uveitis with decreased corneal sensation, which is probably a sequela of Hansen disease.
PY - 2023 T2 - JAMA ophthalmology TI - Moth-Eaten Appearance of the Iris in Hansen Disease. VL - 141 SN - 2168-6173 ER -