Prostaglandins not only have a role in inflammation, but may also be involved as mediators in the immune response. Drugs which affect prostaglandin synthesis may therefore be potential tools with which to modulate disturbed immunity. These possibilities are discussed with reference to immunity in leprosy, and in particular reversal reactions.
BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/2657300?dopt=Abstract CN - Infolep Library - available DA - 1989 Mar DO - 10.5935/0305-7518.19890008 IS - 1 J2 - Lepr Rev LA - eng N2 -Prostaglandins not only have a role in inflammation, but may also be involved as mediators in the immune response. Drugs which affect prostaglandin synthesis may therefore be potential tools with which to modulate disturbed immunity. These possibilities are discussed with reference to immunity in leprosy, and in particular reversal reactions.
PY - 1989 SP - 51 EP - 8 T2 - Leprosy review TI - Prostaglandins and leprosy. A role for aspirin? UR - http://leprev.ilsl.br/pdfs/1989/v60n1/pdf/v60n1a08.pdf VL - 60 SN - 0305-7518 ER -