TY - JOUR KW - Antibodies, Monoclonal KW - Antigens, Bacterial KW - Cell Transformation, Viral KW - Glycolipids KW - Herpesvirus 4, Human KW - Humans KW - leprosy KW - Mycobacterium leprae AU - Moudgil K D AU - Gupta S K AU - Talwar G P AB -

The development of an Epstein-Barr virus transformed human B-cell line secreting a monoclonal antibody (MoAb), KR2/B5 is described. KR2/B5 is an IgM type of antibody and is highly specific for phenolic glycolipid-I (PGL-I) a component unique to M. leprae. The MoAb appears to be directed against the terminal sugar residue of the immunodominant trisaccharide component of PGL-I.

BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/2559933?dopt=Abstract CN - Infolep Library - available DA - 1989 Oct IS - 4 J2 - Indian J Lepr LA - eng N2 -

The development of an Epstein-Barr virus transformed human B-cell line secreting a monoclonal antibody (MoAb), KR2/B5 is described. KR2/B5 is an IgM type of antibody and is highly specific for phenolic glycolipid-I (PGL-I) a component unique to M. leprae. The MoAb appears to be directed against the terminal sugar residue of the immunodominant trisaccharide component of PGL-I.

PY - 1989 SP - 479 EP - 84 T2 - Indian journal of leprosy TI - Generation and characterization of a human monoclonal antibody against phenolic glycolipid-I of M. leprae. VL - 61 SN - 0254-9395 ER -