Mycobacterium leprae is the causative agent of leprosy, a chronic granulomatous disease primarily affecting the skin and peripheral nervous system. M. leprae was the first bacterial pathogen associated with a specific human disease and the only mycobacterium known to cause infection of the nervous tissue. The Koch postulates have never been fulfilled for M. leprae because so far, it has not been cultivated in vitro.
BT - Textbook of Microbiology and Immunology DO - 10.1007/978-981-19-3315-8_31 LA - Eng M3 - Book Chapter N2 -Mycobacterium leprae is the causative agent of leprosy, a chronic granulomatous disease primarily affecting the skin and peripheral nervous system. M. leprae was the first bacterial pathogen associated with a specific human disease and the only mycobacterium known to cause infection of the nervous tissue. The Koch postulates have never been fulfilled for M. leprae because so far, it has not been cultivated in vitro.
PB - Springer Nature Singapore PY - 2023 SN - 9789811933141 SP - 439 EP - 456 T2 - Textbook of Microbiology and Immunology TI - Mycobacterium leprae, Mycobacterium lepraemurium and Non-tuberculosis Mycobacteria ER -