TY - JOUR
KW - Blister
KW - Cell Count
KW - Humans
KW - Immunohistochemistry
KW - leprosy
KW - Leprosy, Borderline
KW - Leprosy, lepromatous
KW - Leprosy, Tuberculoid
KW - Monocytes
KW - T-Lymphocytes, Helper-Inducer
KW - T-Lymphocytes, Regulatory
AU - Rangdaeng S
AU - Scollard D M
AU - Suriyanon V
AU - Smith T
AU - Thamprasert K
AU - Theetranont C
AB - <p>The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis.</p>

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
C1 - <p>http://www.ncbi.nlm.nih.gov/pubmed/2526190?dopt=Abstract</p>

DA - 1989 Jun
IS - 2
J2 - Int. J. Lepr. Other Mycobact. Dis.
LA - eng
N2 - <p>The cellular contents of blisters induced by suction over new, uncomplicated leprosy lesions, and in the skin of cured, control patients, have been examined with enzyme- and immuno-histochemical staining over a period of 4 days. The total cellularity of the blisters varied over a wide range, not correlated with the type of leprosy. Mononuclear cells predominated at all times studied, with nearly equal percentages of monocytes and T lymphocytes. The T-helper: suppressor ratio was significantly greater in BT than in BL and LL lesions at 48 hr. Suction blisters offer a painless, quantitative, reproducible, multiple-sampling method for obtaining cells from the cutaneous infiltrates of leprosy for phenotyping or functional analysis.</p>

PY - 1989
SP - 492
EP - 8
T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
TI - Studies of human leprosy lesions in situ using suction-induced blisters. 1. Cellular components of new, uncomplicated lesions.
UR - http://ila.ilsl.br/pdfs/v57n2a07.pdf
VL - 57
SN - 0148-916X
ER -