TY - JOUR KW - General Energy AU - dos Santos DF AU - Herlys Gomes Braga V AU - Junqueira Oliveira T AU - Sabião Borges I AU - Goulart IMB AB -

A 39-years-old male patient with previously treated borderline lepromatous (BL) leprosy, presented with paresthesia and dysesthesia in the feet and hands, associated with fever, arthralgia, and erythema nodosum during a Type-2 leprosy reaction (LR) episode. This evolved in 3 days to a flaccid tetraparesis with areflexia, with gait impairment, in addition to clinical signs of dysautonomia, such as tachycardia, tachydyspnea, and cranial nerve involvement. The nerve conduction study was compatible with an acute inflammatory demyelinating polyradiculoneuropathy and the cerebrospinal fluid (CSF) analysis confirmed an inflammatory pattern. The patient was treated with intravenous immunoglobulin, showing an important clinical improvement. This case describes the unusual association between leprosy and Guillain-Barré syndrome (GBS), emphasizing the importance of recognition of this condition.

BT - Leprosy Review DO - 10.47276/lr.93.4.420 IS - 4 LA - Eng N2 -

A 39-years-old male patient with previously treated borderline lepromatous (BL) leprosy, presented with paresthesia and dysesthesia in the feet and hands, associated with fever, arthralgia, and erythema nodosum during a Type-2 leprosy reaction (LR) episode. This evolved in 3 days to a flaccid tetraparesis with areflexia, with gait impairment, in addition to clinical signs of dysautonomia, such as tachycardia, tachydyspnea, and cranial nerve involvement. The nerve conduction study was compatible with an acute inflammatory demyelinating polyradiculoneuropathy and the cerebrospinal fluid (CSF) analysis confirmed an inflammatory pattern. The patient was treated with intravenous immunoglobulin, showing an important clinical improvement. This case describes the unusual association between leprosy and Guillain-Barré syndrome (GBS), emphasizing the importance of recognition of this condition.

PB - Lepra PY - 2022 SP - 420 EP - 423 T2 - Leprosy Review TI - Guillain-Barré syndrome following a Type 2 leprosy reaction: A case report UR - https://leprosyreview.org/admin/public/api/lepra/website/getDownload/63947035afaac164c048cb66 VL - 93 SN - 2162-8807 ER -