BACKGROUND: Leprosy, a chronic infectious disease, is one of the major causes of preventable disability. Early treatment prevents neurological damage and disability.
AIM: To identify prognostic factors of disability in individuals with multibacillary and paucibacillary leprosy who completed a drug treatment between 2011 and 2017 in Paraguay.
METHODS: A case-control study was carried out on 34 patients, of them 9 were cases and 25 controls. Cases were those patients with Grade 1, presented lack of sensation in lower or upper limbs, and those of Grade 2 lagophthalmos, rigidity, visible deformity ulcerations, passive claw, active claw. Controls had no disabilities.
RESULTS: Mean age of the patients was 53 ± 15.2 years, 55.9% were male, and 58.9% had primary education or no formal education. Multibacillary leprosy was found in 58.8% of patients; and 64.7% were diagnosed after consulting with two or more physicians. Diagnosis delay of more than one year was significantly (p = 0.047) greater in the cases than in the controls (77.8% vs 12%; OR: 7.44; 95% CI: 1.02-67.86).
CONCLUSION: In this study, a diagnosis delay of more than one year is a prognostic factor for disability.
BT - Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia C1 - https://www.ncbi.nlm.nih.gov/pubmed/34652399 DA - 08/2021 DO - 10.4067/S0716-10182021000400532 IS - 4 J2 - Rev Chilena Infectol LA - spa N2 -BACKGROUND: Leprosy, a chronic infectious disease, is one of the major causes of preventable disability. Early treatment prevents neurological damage and disability.
AIM: To identify prognostic factors of disability in individuals with multibacillary and paucibacillary leprosy who completed a drug treatment between 2011 and 2017 in Paraguay.
METHODS: A case-control study was carried out on 34 patients, of them 9 were cases and 25 controls. Cases were those patients with Grade 1, presented lack of sensation in lower or upper limbs, and those of Grade 2 lagophthalmos, rigidity, visible deformity ulcerations, passive claw, active claw. Controls had no disabilities.
RESULTS: Mean age of the patients was 53 ± 15.2 years, 55.9% were male, and 58.9% had primary education or no formal education. Multibacillary leprosy was found in 58.8% of patients; and 64.7% were diagnosed after consulting with two or more physicians. Diagnosis delay of more than one year was significantly (p = 0.047) greater in the cases than in the controls (77.8% vs 12%; OR: 7.44; 95% CI: 1.02-67.86).
CONCLUSION: In this study, a diagnosis delay of more than one year is a prognostic factor for disability.
PY - 2021 SP - 532 EP - 539 T2 - Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia TI - Delay in diagnosis as a prognostic factor for disability in patients with leprosy in Paraguay. Case and control study. UR - https://www.scielo.cl/pdf/rci/v38n4/0716-1018-rci-38-04-0532.pdf VL - 38 SN - 0717-6341 ER -