TY - JOUR KW - Animals KW - Dapsone KW - Drug Resistance, Microbial KW - Humans KW - leprosy KW - Mice KW - Mice, Inbred CBA KW - Mycobacterium leprae KW - Philippines AU - Guinto R S AU - Cellona R V AU - Fajardo T T AU - Cruz E C AB -
A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3.6 per 100. Fifty-three of 55 patients proved to have M. leprae fully susceptible to dapsone. The organisms of two patients multiplied in mice administered the minimal effective dose of dapsone; and those of one of these patients also multiplied in mice administered dapsone in a 10-fold larger dose.
BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 -http://www.ncbi.nlm.nih.gov/pubmed/7042607?dopt=Abstract
DA - 1981 Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3.6 per 100. Fifty-three of 55 patients proved to have M. leprae fully susceptible to dapsone. The organisms of two patients multiplied in mice administered the minimal effective dose of dapsone; and those of one of these patients also multiplied in mice administered dapsone in a 10-fold larger dose.
PY - 1981 SP - 427 EP - 30 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Primary dapsone-resistant leprosy in Cebu, Philippines. UR - http://ila.ilsl.br/pdfs/v49n4a07.pdf VL - 49 SN - 0148-916X ER -