Erythema nodosum leprosum (ENL) is the commonest manifestation of type 2 lepra reaction (T2LR) due to immune complex mediated inflammation in patients of lepromatous (LL) and borderline lepromatous (BL) leprosy. Vaccines given as immunotherapy in leprosy may expedite early smear negativity and may hasten complete recovery. However, vaccination can also be associated with reactions. Majority of vaccine induced lepra reactions were reported about five decades back in the era of smallpox vaccination.
BT - Journal of the European Academy of Dermatology and Venereology : JEADV C1 - https://www.ncbi.nlm.nih.gov/pubmed/33587765 DA - 02/2021 DO - 10.1111/jdv.17176 J2 - J Eur Acad Dermatol Venereol LA - eng N2 -Erythema nodosum leprosum (ENL) is the commonest manifestation of type 2 lepra reaction (T2LR) due to immune complex mediated inflammation in patients of lepromatous (LL) and borderline lepromatous (BL) leprosy. Vaccines given as immunotherapy in leprosy may expedite early smear negativity and may hasten complete recovery. However, vaccination can also be associated with reactions. Majority of vaccine induced lepra reactions were reported about five decades back in the era of smallpox vaccination.
PY - 2021 T2 - Journal of the European Academy of Dermatology and Venereology : JEADV TI - Recurrent Erythema Nodosum Leprosum Associated With Mycobacterium Indicus Pranii Vaccine In A Case Of Leprosy: A Rare paradox. SN - 1468-3083 ER -