Palmoplantar involvement has been infrequently reported in leprosy and is an easily misdiagnosed entity. The institutional database of leprosy clinic from 2015 to 2018 was accessed. Details pertaining to demography, clinical presentation, comorbidities (if any), treatment received, and outcome were analyzed in leprosy patients with palmoplantar involvement. Among the 520 patients studied, the involvement of palms and/or soles was reported in 49 (9.4%) patients. Isolated palm involvement was the most frequent (26/49, 53.1%), followed by both palm and sole involvement (12/49, 24.5%) and sole involvement alone (11/49, 22.4%). A higher incidence of lepra reactions and disabilities was noted in patients with palmoplantar involvement than in those without (P < 0.0001). Palmoplantar involvement in leprosy, although uncommon, is associated with a higher risk of reactions and disabilities. A knowledge of this end of the spectrum can help in maintaining a high index of suspicion and reduce misdiagnosis.
BT - The American journal of tropical medicine and hygiene C1 - https://www.ncbi.nlm.nih.gov/pubmed/33591935 DA - 02/2021 DO - 10.4269/ajtmh.19-0598 J2 - Am J Trop Med Hyg LA - eng N2 -Palmoplantar involvement has been infrequently reported in leprosy and is an easily misdiagnosed entity. The institutional database of leprosy clinic from 2015 to 2018 was accessed. Details pertaining to demography, clinical presentation, comorbidities (if any), treatment received, and outcome were analyzed in leprosy patients with palmoplantar involvement. Among the 520 patients studied, the involvement of palms and/or soles was reported in 49 (9.4%) patients. Isolated palm involvement was the most frequent (26/49, 53.1%), followed by both palm and sole involvement (12/49, 24.5%) and sole involvement alone (11/49, 22.4%). A higher incidence of lepra reactions and disabilities was noted in patients with palmoplantar involvement than in those without (P < 0.0001). Palmoplantar involvement in leprosy, although uncommon, is associated with a higher risk of reactions and disabilities. A knowledge of this end of the spectrum can help in maintaining a high index of suspicion and reduce misdiagnosis.
PY - 2021 T2 - The American journal of tropical medicine and hygiene TI - Palmoplantar Involvement in Leprosy: A Clinicopathological Study. UR - https://www.ajtmh.org/view/journals/tpmd/aop/article-10.4269-ajtmh.19-0598/article-10.4269-ajtmh.19-0598.xml?tab_body=pdf SN - 1476-1645 ER -