TY - JOUR
KW - Adolescent
KW - Adult
KW - Age Factors
KW - Aged
KW - Aged, 80 and over
KW - Antigens, Bacterial
KW - Brazil
KW - Child
KW - Child, Preschool
KW - Cross-Sectional Studies
KW - Family
KW - Female
KW - Humans
KW - Infant
KW - leprosy
KW - Male
KW - Middle Aged
KW - Mycobacterium leprae
KW - Risk Factors
KW - Seroepidemiologic Studies
KW - Sex Factors
KW - Young Adult
AU - Andrade ARC
AU - Faria Grossi MA
AU - Bührer-Sékula S
AU - Antunes CMF
AB - <p>Leprosy is a public health problem in Brazil. Epidemiological control actions are based on the diagnosis and treatment of leprosy patients and household contact surveillance. Serological tests for leprosy could identify from among the contacts those at greater risk of developing leprosy in the future. ML Flow was administered to 2,840 household contacts of new leprosy cases diagnosed from October 2002 to March 2004, in State of Minas Gerais. ML Flow was positive in 20.5% of leprosy contacts, with high seropositivity among males (22.4%), individuals aged over 15 years-old (21.7%) and individuals in contact with multibacillary cases (23.9%). The chances of a household contact presenting a seropositive test was related to household contact with a multibacillary index case (OR=1.75), age over 15 years-old (OR=1.38) and male gender (OR=1.25). Follow-up of these contacts is necessary to evaluate the real role of seropositivity in the development of leprosy disease.</p>
BT - Revista da Sociedade Brasileira de Medicina Tropical
C1 - http://www.ncbi.nlm.nih.gov/pubmed/19618077?dopt=Abstract
DA - 2008
DO - 10.1590/s0037-86822008000700012
J2 - Rev. Soc. Bras. Med. Trop.
LA - eng
N2 - <p>Leprosy is a public health problem in Brazil. Epidemiological control actions are based on the diagnosis and treatment of leprosy patients and household contact surveillance. Serological tests for leprosy could identify from among the contacts those at greater risk of developing leprosy in the future. ML Flow was administered to 2,840 household contacts of new leprosy cases diagnosed from October 2002 to March 2004, in State of Minas Gerais. ML Flow was positive in 20.5% of leprosy contacts, with high seropositivity among males (22.4%), individuals aged over 15 years-old (21.7%) and individuals in contact with multibacillary cases (23.9%). The chances of a household contact presenting a seropositive test was related to household contact with a multibacillary index case (OR=1.75), age over 15 years-old (OR=1.38) and male gender (OR=1.25). Follow-up of these contacts is necessary to evaluate the real role of seropositivity in the development of leprosy disease.</p>
PY - 2008
SP - 56
EP - 9
T2 - Revista da Sociedade Brasileira de Medicina Tropical
TI - Seroprevalence of ML Flow test in leprosy contacts from State of Minas Gerais, Brazil.
VL - 41 Suppl 2
SN - 1678-9849
ER -