TY - JOUR KW - Adolescent KW - Adult KW - Africa KW - Aged KW - Chi-Square Distribution KW - Female KW - HIV Antibodies KW - HIV Infections KW - HIV-1 KW - HIV-2 KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Prevalence KW - Risk Factors KW - Yemen AU - Léonard G AU - Sangare A AU - Verdier M AU - Sassou-Guesseau E AU - Petit G AU - Milan J AU - M'Boup S AU - Rey J L AU - Dumas J L AU - Hugon J AB -

Screening for human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) antibodies was carried out in the serum of 1,245 leprous patients and 5,731 controls selected in nine different centers from the Congo, Ivory Coast, Senegal, and Yemen Arab Republic. In Yemen, all sera were negative. In the Congo, the seropositivity among patients and controls was, respectively, 3.8 and 5.2%; in Senegal, it was 1.3 and 0.6%; and in the Ivory Coast 4.8 and 3.9%. Differences were not statistically significant, even considering lepromatous or tuberculoid forms (3.6% and 3.7%, respectively). HIV-2 antibodies were only detected in subjects from the Ivory Coast and Senegal. Using appropriate criteria for seropositivity (confirmation by Western blot, reactivity to HIV envelope glycoproteins) and a large selection of patients (several countries with several centers), it appears that leprosy (and specially the lepromatous form) is not a factor for HIV infection.

BT - Journal of acquired immune deficiency syndromes C1 - http://www.ncbi.nlm.nih.gov/pubmed/2213512?dopt=Abstract DA - 1990 IS - 11 J2 - J. Acquir. Immune Defic. Syndr. LA - eng N2 -

Screening for human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) antibodies was carried out in the serum of 1,245 leprous patients and 5,731 controls selected in nine different centers from the Congo, Ivory Coast, Senegal, and Yemen Arab Republic. In Yemen, all sera were negative. In the Congo, the seropositivity among patients and controls was, respectively, 3.8 and 5.2%; in Senegal, it was 1.3 and 0.6%; and in the Ivory Coast 4.8 and 3.9%. Differences were not statistically significant, even considering lepromatous or tuberculoid forms (3.6% and 3.7%, respectively). HIV-2 antibodies were only detected in subjects from the Ivory Coast and Senegal. Using appropriate criteria for seropositivity (confirmation by Western blot, reactivity to HIV envelope glycoproteins) and a large selection of patients (several countries with several centers), it appears that leprosy (and specially the lepromatous form) is not a factor for HIV infection.

PY - 1990 SP - 1109 EP - 13 T2 - Journal of acquired immune deficiency syndromes TI - Prevalence of HIV infection among patients with leprosy in African countries and Yemen. VL - 3 SN - 0894-9255 ER -