This paper briefly describes organizational, operational, and sociocultural aspects of the phase-III clinical trials of the ICRC anti-leprosy vaccine in Maharashtra, India. Our experience is that vaccine trials can be launched quickly and more cost effectively by using the services of health personnel from the existing public health infrastructure. That is why the trials could be launched in just 4 months after receiving the financial grant from the Indian Council of Medical Research, New Delhi (India). At the community level, a person-to-person approach in Health Education scores over audio-visual aids and the mass media. The compliance in target groups is increased when preventive programmes are backed-up by curative services and when their privacy and daily routine are not disturbed.
BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/2181223?dopt=Abstract CN - Infolep Library - available DA - 1990 Mar DO - 10.5935/0305-7518.19900006 IS - 1 J2 - Lepr Rev LA - eng N2 -This paper briefly describes organizational, operational, and sociocultural aspects of the phase-III clinical trials of the ICRC anti-leprosy vaccine in Maharashtra, India. Our experience is that vaccine trials can be launched quickly and more cost effectively by using the services of health personnel from the existing public health infrastructure. That is why the trials could be launched in just 4 months after receiving the financial grant from the Indian Council of Medical Research, New Delhi (India). At the community level, a person-to-person approach in Health Education scores over audio-visual aids and the mass media. The compliance in target groups is increased when preventive programmes are backed-up by curative services and when their privacy and daily routine are not disturbed.
PY - 1990 SP - 50 EP - 9 T2 - Leprosy review TI - The sociocultural dimension in leprosy vaccine trials. UR - http://leprev.ilsl.br/pdfs/1990/v61n1/pdf/v61n1a06.pdf VL - 61 SN - 0305-7518 ER -