Erythema Nodosum Leprosum (ENL) is an immune complex-mediated reaction that may complicate the course of lepromatous and borderline lepromatous cases of leprosy. Severe ENL can become vesicular or bullous and very rarely breakdown into an ulcerative skin lesions and is termed as Erythema Necroticans (ENe). It generally occurs during the course of multidrug therapy, though its de novo occurrence has been reported. Prompt recognition of this condition and specific treatment is essential to reduce the morbidity and community burden associated with leprosy.
BT - QJM : monthly journal of the Association of Physicians C1 - https://www.ncbi.nlm.nih.gov/pubmed/31860095 DA - 12/2019 DO - 10.1093/qjmed/hcz323 J2 - QJM LA - eng N2 -Erythema Nodosum Leprosum (ENL) is an immune complex-mediated reaction that may complicate the course of lepromatous and borderline lepromatous cases of leprosy. Severe ENL can become vesicular or bullous and very rarely breakdown into an ulcerative skin lesions and is termed as Erythema Necroticans (ENe). It generally occurs during the course of multidrug therapy, though its de novo occurrence has been reported. Prompt recognition of this condition and specific treatment is essential to reduce the morbidity and community burden associated with leprosy.
PY - 2019 T2 - QJM : monthly journal of the Association of Physicians TI - Erythema necroticans. UR - https://academic.oup.com/qjmed/advance-article/doi/10.1093/qjmed/hcz323/5682419 SN - 1460-2393 ER -