TY - JOUR KW - Antibodies, Bacterial KW - Antigens, Bacterial KW - Disaccharides KW - Enzyme-Linked Immunosorbent Assay KW - Glycolipids KW - Humans KW - Immunoglobulin G KW - Immunoglobulin M KW - leprosy KW - Mycobacterium leprae KW - Mycobacterium tuberculosis KW - Trehalose AU - Cruaud P AU - Potar M C AU - David H L AU - Papa F AU - Torgal-Garcia J AU - Maroja F AU - Orsi-Souza A T AB -

The distribution of IgG and IgM antibodies immunoreacting with the sulpholipid I (SLI) and sulpholipid IV (SLIV) of Mycobacterium tuberculosis was examined in sera from leprosy patients. It was found that the immunological reactions correlated with the clinical spectrum of leprosy; and in multibacillary patients, antibody titres declined in response to successful treatment. The serological patterns were similar to the PGL I patterns, however, the IgG responses towards the sulpholipids were predominant over the IgM responses in the case of the sulpholipid antigens.

BT - Zentralblatt fur Bakteriologie : international journal of medical microbiology C1 - http://www.ncbi.nlm.nih.gov/pubmed/2119181?dopt=Abstract DA - 1990 Jun DO - 10.1016/s0934-8840(11)80251-3 IS - 2 J2 - Zentralbl. Bakteriol. LA - eng N2 -

The distribution of IgG and IgM antibodies immunoreacting with the sulpholipid I (SLI) and sulpholipid IV (SLIV) of Mycobacterium tuberculosis was examined in sera from leprosy patients. It was found that the immunological reactions correlated with the clinical spectrum of leprosy; and in multibacillary patients, antibody titres declined in response to successful treatment. The serological patterns were similar to the PGL I patterns, however, the IgG responses towards the sulpholipids were predominant over the IgM responses in the case of the sulpholipid antigens.

PY - 1990 SP - 209 EP - 15 T2 - Zentralblatt fur Bakteriologie : international journal of medical microbiology TI - IgG and IgM antibodies immunoreacting with a 2,3-diacyl trehalose-2'-sulphate in sera from leprosy patients. VL - 273 SN - 0934-8840 ER -