TY - JOUR KW - Adolescent KW - Adult KW - Antibodies, Bacterial KW - Child KW - Child, Preschool KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Humans KW - Immunity, Cellular KW - Immunoglobulin M KW - Lepromin KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae AU - Dhandayuthapani S AU - Anandan D AU - Bhatia V N AB -
A total of 438 household contacts of leprosy patients and 228 non-contacts were studied for anti-PGL-I antibodies and cell mediated immune response to Mycobacterium leprae using ELISA and lepromin tests. The contacts showed relatively higher positivity to ELISA (29.4%) and lepromin (70.5%) as compared to non-contacts who showed 9.6 and 57 per cent positivity. In contacts as well as non-contacts the seropositivity was not found to be influenced by age and sex. However, seropositivity was higher (39.7%) in the contacts of patients with multibacillary leprosy as compared to contacts (27.7%) of patients with paucibacillary leprosy.
BT - The Indian journal of medical research C1 - http://www.ncbi.nlm.nih.gov/pubmed/2091988?dopt=Abstract DA - 1990 Nov J2 - Indian J. Med. Res. LA - eng N2 -A total of 438 household contacts of leprosy patients and 228 non-contacts were studied for anti-PGL-I antibodies and cell mediated immune response to Mycobacterium leprae using ELISA and lepromin tests. The contacts showed relatively higher positivity to ELISA (29.4%) and lepromin (70.5%) as compared to non-contacts who showed 9.6 and 57 per cent positivity. In contacts as well as non-contacts the seropositivity was not found to be influenced by age and sex. However, seropositivity was higher (39.7%) in the contacts of patients with multibacillary leprosy as compared to contacts (27.7%) of patients with paucibacillary leprosy.
PY - 1990 SP - 431 EP - 6 T2 - The Indian journal of medical research TI - ELISA & lepromin skin tests in household contacts of leprosy patients. VL - 91 SN - 0971-5916 ER -